Concentrations of L- and D-lactate in serum, urine, and rumen liquid in calves, with special reference to ruminal drinkers

Grude, T.

Tierarztliche Praxis Ausgabe G, Grosstiere/Nutztiere 31(2): 72-77


ISSN/ISBN: 1434-1220
Accession: 003690575

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The objective of this prospective clinical study was to examine certain aspects of lactate metabolism in calves with and without evidence of ruminal drinking (Germany). A total of 81 calves up to four weeks of age, in which blood, urine and rumen liquid samples could be taken upon admission were included in the study. The following were determined: Concentrations of D- and L-lactate in blood, urine, and rumen liquid; pH, base excess (BE), anion gap, concentrations of HCO3- and urea in venous blood; specific gravity and creatinine concentration in urine; pH and chloride concentration in rumen liquid. On the basis of base excess (BE) in venous blood and ruminal pH, calves were allocated to one of four groups: Group A: control group (BE 0+or-5 mmol/l, ruminal pH>=6.0); Group B: ruminal acidosis (BE 0+or-5 mmol/l, ruminal pH<6.0); Group C: systemic acidosis (BE<-5 mmol/l, ruminal pH>=6.0); Group D: systemic and ruminal acidosis (BE<-5 mmol/l, ruminal pH<6.0). Elevated levels of D-lactate in the rumen were not consistently associated with raised serum lactate levels or systemic lactic acidosis. Both findings did occur, however. The source of D-lactate could not be identified.