Controversy concerning optimal prophylaxis and empirical antifungal therapy in immunocompromised patients
Controversy concerning optimal prophylaxis and empirical antifungal therapy in immunocompromised patients
Zielińska, E.
Przeglad Epidemiologiczny 57(2): 299-307
2003
ISSN/ISBN: 0033-2100
PMID: 12910598
A steady increase in the frequency of opportunistic invasive fungal infections (IFIs) in immunocompromised patients is considered as a major problem. However, there still remains much uncertainty regarding the best methods for establishing the diagnosis of most IFIs. An international consensus proposed three levels of probability in defining opportunistic IFIs: proven, probable, and possible. Practicing physicians approach this uncertainty by prophylaxis and antifungal empirical therapy.