EurekaMag.com logo
+ Site Statistics
References:
48,252,460
Abstracts:
22,798,453
+ Resolve Accession
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
Submit PDF Full TextSubmit PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Cytochrome P450 differences in normal and imposex-affected female whelk Buccinum undatum from the open North Sea


, : Cytochrome P450 differences in normal and imposex-affected female whelk Buccinum undatum from the open North Sea. ine Environmental Research ember- ember; 54(3-5): 661-665

Normal and imposex-affected female Buccinum undatum were sampled from the open North Sea at three locations, one with low, and two with high shipping densities. Cytochrome P450 components and P450 aromatase activity were determined in the microsomal fractions isolated from pooled digestive gland/gonads. Cytochrome P450 aromatase activity was significantly higher (P&< 0.05) in normal females collected in the low shipping density area (1325[plus or minus] 295 fmol/h/mg protein) than levels from imposex animals from a high shipping density area (620[plus or minus]287 fmol/h/mg protein). A negative correlation was found between aromatase activity andorganotin body burden (r=-0.99). Levels of CYP450, cytochrome b5 and NADPH cytochrome c reductase activity did not show differences among groups. This is the first field evidence of depressed aromatase activity in imposex affected females, although additional research under laboratory controlled conditions is required to fully understand the mechanisms underlying the development of imposex in this species.

Order PDF Full Text

Close
Close

Click here to order any other PDF Full Text


Accession: 003699500

PMID: 12408632

DOI: 10.1016/s0141-1136(02)00150-2

Download PDF Full Text: Cytochrome P450 differences in normal and imposex-affected female whelk Buccinum undatum from the open North Sea


Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:
Close
Close

Other references

Saha, A.K., 1969: Benign congenital parotid haemangioma. Report of a case in an infant. Indian Journal of Pediatrics 36(260): 328-329

Saltz, L., 2014: Systemic therapy for metastatic colorectal cancer. In the treatment of advanced colorectal cancer (CRC), the addition of so-called "targeted" agents to irinotecan- and oxaliplatin-based regimens has resulted in statistically significant--but often clinically modest--improvements in progr...

Barraza, P.; Vera, P., 1971: Gynecological injuries in childhood. Revista Chilena de Pediatria 42(1): 33-35

Rooks, W.H.; Maloney, P.J.; Shott, L.D.; Schuler, M.E.; Sevelius, H.; Strosberg, A.M.; Tanenbaum, L.; Tomolonis, A.J.; Wallach, M.B.; Waterbury, D., 1985: The analgesic and anti-inflammatory profile of ketorolac and its tromethamine salt. Ketorolac tromethamine[(+/-)-5(benzoyl)-2,3-dihydro-1N-pyrrolizine-1-carboxylic acid tris hydroxymethylaminomethane salt] is a highly potent member of a new class of compounds having analgesic and anti-inflammatory activity. When given orally in t...

Zamprogno, C.; Das Gracas Zamprogno, M., 1997: Siphonops hardyi (Hardy's caecilian). Herpetological Review 28.2: 92

Buades, J.; Ben-Chetrit, E.; Levy, M., 1995: Familial Mediterranean fever in the "Chuetas" of Mallorca--origin in inquisition?. The aim of our study was to compare the features of familial Mediterranean fever (FMF) in Mallorcan "Chuetas" with those in non-Ashkenazi Jews in Israel. The clinical and laboratory data of FMF were evaluated in a recently identified clu...

Hall, K.T.; Giles, M.S.; Goodwin, D.J.; Calderwood, M.A.; Carr, I.M.; Stevenson, A.J.; Markham, A.F.; Whitehouse, A., 2000: Analysis of gene expression in a human cell line stably transduced with herpesvirus saimiri. Herpesvirus saimiri (HVS) is the prototype gamma-2 herpesvirus; it has significant homology to the human gammaherpesviruses Kaposi's sarcoma-associated virus and Epstein-Barr virus and the murine gammaherpesvirus murine herpesvirus 68. HVS ca...

Jia Jia, 2003: Prospects for treatment of falciparum malaria. The difficulty in treating malaria caused by Plasmodium falciparum lies in the fact that the parasites can easily become tolerant to new drugs and they spread very rapidly. Existing major drugs include chloroquine, fansidar, quinine/quinidine, hal...

Abdelnoor, A.M.; Dhib-Jalbut, S.S.; Tamer, H.K.; Haddad, F.S., 1983: Immune complexes in subacute sclerosing panencephalitis. Progress in Brain Research 59: 145-148

Miyake, H.; Maeda, K.; Asai, N.; Shibata, R.; Ichimiya, H.; Isotani-Sakakibara, M.; Yamamura, Y.; Kato, K.; Enomoto, A.; Takahashi, M.; Murohara, T., 2011: The actin-binding protein Girdin and its Akt-mediated phosphorylation regulate neointima formation after vascular injury. It is well established that the migration and proliferation of vascular smooth muscle cells (VSMCs) have major roles in the vascular remodeling process. Our previous study showed that the Akt substrate Girdin, which is expressed in VSMCs and endot...