+ Translate
+ Most Popular
Investigations on the organic drift in North Swedish streams
Limitations of Using Microsoft Excel Version 2016 (MS Excel 2016) for Statistical Analysis for Medical Research
Phloem necrosis of coffee in Surinam
Anatomy of Mystus seenghala IV Nervous system
Integrated farming system for gardenland conditions of Coimbatore district - an over view
Tetrapleure (Tetrapleura tetraptera), an unknown African medicinal and spice plant
The origin and phylogenetic significance of the trochophoran larvae 2. evolutionary significance of the larvae of coelomate worms and mollusks
Comparison of rice bran and maize bran as feeds for growing and fattening pigs
Enterobacter amnigenus. An unusual human pathogen
Influence of Seriboost foliar application on leaf yield and leaf protein content in mulberry (Morus spp.), in relation to silkworm cocoon production
The identity of the lipstick mold of cultivated mushrooms agaricus bisporus
Advantages and disadvantages of bordeaux mixture and of lime-sulphur used on apples in the growing season
'Pan-sukh' disease of Rice in the Central Provinces
Geological age of the Ptilophyllum flora; a critical reassessment
Study of vitellogenesis in birds; physiological phases & role of folliculin in vitellogenesis
Evaluation of WCT coconut and Komadan coconut
Therapy for acne with saccharomyces boulardii
Evidence for Late Cretaceous N-S dextral shear in the west-central crystalline core, North Cascades, Washington
'Rajeshwari' - a high-yielding white seeded variety of sesame for Andhra Pradesh
Manufacture of Ricotta cheese from whey fortified with skim milk powder using different acidulants
Occurrence of Eutrichophilus mexicanus (Rudow, 1866) and Eutrichophilus lobatus (Ewing, 1936) (Phthiraptera: Trichodectidae) on Sphiggurus villosus (Cuvier, 1825) (Rodentia: Erethizontidae) in Rio de
Factors affecting fruitfulness in durian (Durio zibethinus Murr.). I. Flowering and pollination
Bronchial cuff pressure change caused by left-sided double-lumen endobronchial tube displacement
Some Biological Applications of Organometallic Compounds
The composition of pampas-grass (Cortaderia argentea.)

Cytochromes P450 of insects: the tip of the iceberg

Cytochromes P450 of insects: the tip of the iceberg

Pest Management Science 57(10): 958-967

ISSN/ISBN: 1526-498X

PMID: 11695190

DOI: 10.1002/ps.354

The cytochrome P450-dependent monooxygenases are an extremely important metabolic system involved in the metabolism of endogenous compounds and xenobiotics. Collectively, P450 monooxygenases can metabolize numerous substrates and carry out multiple oxidative reactions. The large number of substrates metabolized is due to the plethora of P450 isoforms and to the broad substrate specificity of some isoforms. Monooxygenases of insects have several functional roles, including growth, development, feeding and protection against xenobiotics, including resistance to pesticides and tolerance to plant toxins. This review begins with background information about P450s and their evolution, followed by a discussion of the extraordinary diversity of insect P450s. Given the enormous interest in studying individual P450s, we then provide a synopsis of the different methods that have been used in their isolation and the substrates that are known to be metabolized. We conclude by summarizing the lessons we have learned from the study of individual insect P450s, including their roles in insecticide resistance, plant-insect interactions and insect physiology. However, these studies are just the 'tip of the iceberg'. Our knowledge continues to expand at a rapid pace, suggesting that the next decade will outpace the last in terms of improving our understanding of the cytochromes P450 of insects.

Please choose payment method:

(PDF emailed within 0-6 h: $19.90)

Accession: 003699524

Download citation: RISBibTeXText

Related references

Live insects and other arthropods on California iceberg head and shredded lettuce. Southwestern Entomologist 163: 261-266, 1991

Comparison of cytochromes b5 from insects and vertebrates. Proteins 67(2): 293-304, 2007

ICESat profiles of tabular iceberg margins and iceberg breakup at low latitudes. Geophysical Research Letters 32(23, 2005, 2005

Iceberg furrowing and pitting by a single iceberg grounding event on the Grand Banks of Newfoundland. Program with Abstracts - Geological Association of Canada 15: 101, 1990

Small icebergs and iceberg fragments off Newfoundland: Relationships to deterioration mechanisms and the regional iceberg population. Atmosphere-Ocean 34(3): 549-579, 1996

Modelling twentieth century global ocean circulation and iceberg flux at 48N: implications for west Greenland iceberg discharge. Progress in Oceanography 138: 194-210, 2015

Iceberg scours, iceberg gravity craters and current erosion marks from a gigantic Proboreal flood in southeastern Norway. Boreas 20(1): 47-62, 1991

Implications of iceberg dynamics for iceberg stability estimation. Cold Regions Science and Technology 22(2): 197-203, 1994

An iceberg drift and decay model to compute the ice-rafted debris and iceberg meltwater flux; application to the interglacial North Atlantic. Paleoceanography: 729-742, 1996

Studies on red and white muscles of insects, with special reference to spectro-photometric observations of cytochromes in muscles. Bulletin NATL INST AGRIC Science JAPAN Ser C(13): 47-55, 1961

Sensitivity of the glacial ocean to Heinrich events from different iceberg sources, as modeled by a coupled atmosphere-iceberg-ocean model. Paleoceanography 23.4, 2008

Comparison of trends of iceberg scour marks with iceberg trajectories and evidence of paleocurrent trends on Saglek Bank, northern Labrador Shelf. Canadian Journal of Earth Sciences = Journal Canadien des Sciences de la Terre 25(9): 1374-1383, 1988

Iceberg dynamics and the impact of drifting icebergs on benthos and fish fauna; Iceberg dynamics. Berichte zur Polar- und Meeresforschung = Reports on Polar and Marine Research 402: 58-62, 2001

Alkylation of cytochromes c. II. Carboxymethylation of beef and human cytochromes c in the oxidized and reduced forms. Biochimica et Biophysica Acta 118(2): 256-267, 1966

Conformational and functional studies of chemically modified cytochromes: N-bromosuccinimide- and formyl-cytochromes c. Biochemistry 14(2): 382-391, 1975