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Cytometric evaluation of peripheral blood lymphocytes in dogs with lymphoma during chemotherapy


Cytometric evaluation of peripheral blood lymphocytes in dogs with lymphoma during chemotherapy



Journal of Veterinary Medicine. A Physiology Pathology Clinical Medicine 49(6): 303-306



ISSN/ISBN: 0931-184X

PMID: 12227473

DOI: 10.1046/j.1439-0442.2002.00455.x

Twenty dogs with clinically diagnosed multicentric lymphoma were evaluated for percentages of peripheral blood lymphocyte subpopulations. Cytometric analysis was performed before and during chemotherapy. The results were compared to those obtained from a control group of healthy dogs. The percentages of CD5+, CD4+ and CD8+ cells were markedly decreased and CD21-like+ cells markedly increased in dogs with lymphoma in comparison with the control group. During the course of chemotherapy these values returned to ranges observed in healthy animals.

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Accession: 003699805

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