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Developmental regulation of apolipoprotein B mRNA editing is an autonomous function of small intestine involving homeobox gene Cdx1


Developmental regulation of apolipoprotein B mRNA editing is an autonomous function of small intestine involving homeobox gene Cdx1



Journal of Biological Chemistry 278(9): 7600-7606



ISSN/ISBN: 0021-9258

PMID: 12493769

DOI: 10.1074/jbc.m201601200

Apolipoprotein B mRNA editing is developmentally regulated in the human and rodent small intestine, changing from <1% at day 14 to ~90% by day 20 in the rat fetus. This regulation is coincident with the developmental formation of the crypt-to-villus axis functional unit, a continuous and rapidly renewing system involving cell generation, migration and differentiation.

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Accession: 003710582

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Related references

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