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Dietary glycine prevents chemical-induced experimental colitis in the rat

Dietary glycine prevents chemical-induced experimental colitis in the rat

Gastroenterology 125(3): 775-785

ISSN/ISBN: 0016-5085

PMID: 12949723

DOI: 10.1016/s0016-5085(03)01067-9

Background and aims: In this study, the effect of dietary glycine on experimental colitis induced by 2,4,6-trinitrobenzene sulphonic acid (TNBS) and dextran sulfate sodium (DSS) in the rat was evaluated. Methods: Male Wistar rats were fed a diet containing 5% glycine or casein as controls starting 3 days before experiments, and were given a single intracolonic injection of TNBS (50 mg/rat, dissolved in 50% ethanol).

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Accession: 003712135

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