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Dietary psoralens induce hepatotoxicity in C57 mice

Dietary psoralens induce hepatotoxicity in C57 mice

Journal of Natural Toxins 9(2): 179-195

ISSN/ISBN: 1058-8108

PMID: 10868344

The psoralens are secondary plant metabolites found in many fruits and vegetables. Synthetic forms of 5-methoxypsoralen (bergapten) and 8-methoxypsoralen (xanthotoxin) have been used in combination with UV radiation in skin photochemotherapy for decades. However, handling or ingestion of psoralen-containing plants as well as medicinal use of these compounds have been shown to cause human health hazards.

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Accession: 003712449

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