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Disposition of cyclosporine after intravenous and multi-dose oral administration in cats

Disposition of cyclosporine after intravenous and multi-dose oral administration in cats

Journal of Veterinary Pharmacology and Therapeutics 26(5): 349-354

ISSN/ISBN: 0140-7783

PMID: 14633187

DOI: 10.1046/j.1365-2885.2003.00496.x

The aim of this study was to evaluate the disposition of cyclosporine (Sandimmune) after intravenous and oral administration and to evaluate single sampling times for therapeutic monitoring of cyclosporine drug concentrations in cats. Six adult male cats (clinically intact) were used. Two treatments consisting of a single iv cyclosporine (1 mg/kg) and multiple oral cyclosporine (3 mg/kg b.i.d po for 2 weeks) doses.

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Accession: 003715595

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