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Effect of anticoagulants on the susceptibility of Aedes aegypti mosquitoes to dengue virus infection


Effect of anticoagulants on the susceptibility of Aedes aegypti mosquitoes to dengue virus infection



Acta Virologica 46(1): 51-53



ISSN/ISBN: 0001-723X

PMID: 12197636

Dengue 2 virus isolated from a patient from Jammu, India with dengue haemorrhagic fever was utilized. Different concentrations of heparin sulfate (625 IU/ml, 250 IU/ml and 50 IU/ml) and EDTA (69 IU/ml, 35 IU/ml and 17 IU/ml) were added to feeding suspensions prepared from a mixture of fowl blood and dengue virus. A. aegypti mosquitoes were fed on defibrinated fowl blood containing the standard virus dose. On day 10 post-infection, the mosquito positivity was determined.

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Accession: 003724815

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