Effect of bioflavonoids extracted from the bark of Pinus maritima on proinflammatory cytokine interleukin-1 production in lipopolysaccharide-stimulated RAW 264.7
Effect of bioflavonoids extracted from the bark of Pinus maritima on proinflammatory cytokine interleukin-1 production in lipopolysaccharide-stimulated RAW 264.7
The mode of action of pycnogenol (PYC), extracted from the bark of Pinus maritima on lipopolysaccharide (LPS)-induced interleukin-1 beta (IL-1 beta ) gene expression was studied. Results demonstrated that PYC blocks both nuclear factor kappa B and activated protein-1 activation in LPS-stimulated RAW 264.7 cells.