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Effect of chronic ethanol administration on the thiamine profile in the blood and tissue of Wistar rats


Effect of chronic ethanol administration on the thiamine profile in the blood and tissue of Wistar rats



Vitamine und Zusatzstoffe in der Ernahrung von Mensch und Tier 8 Symposium, 26 und 27 September, 2001, Jena/Thuringen, Germany: 373-376



In tissues with high energy requirements like the nervous system, thiamine plays an essential role in maintaining the normal physiological activity. Thiamine deficiency is often related to chronic ethanol consumption. The contribution of thiamine deficiency to the pathology of ethanol-related brain damage is discussed. The effect of a long-term ethanol administration (3 and 12 months) on the thiamine status and profile in the blood and brain tissue was studied using 28 male Wistar rats.

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