EurekaMag
+ Translate
+ Most Popular
Advantages and disadvantages of bordeaux mixture and of lime-sulphur used on apples in the growing season
Observations on the Umaria marine bed
10 years of hearing conservation in the Royal Air Force
Chocolate crumb - dairy ingredient for milk chocolate
Effect of daily gelatin ingestion on human scalp hair
Comparison of rice bran and maize bran as feeds for growing and fattening pigs
The composition of pampas-grass (Cortaderia argentea.)
The Accraian Series:
The mechanism of the Liebermann-Burchard reaction of sterols and triterpenes and their esters
Cerebrovascular Doppler ultrasound studies (cv-Doppler)
Toria: PT-303 - first national variety
Hair growth promoting activity of tridax procumbens
Productivity of Pekin x Khaki Campbell ducks
A stable cytosolic expression of VH antibody fragment directed against PVY NIa protein in transgenic potato plant confers partial protection against the virus
Solar treatment of wheat loose smut
Swimmers itch in the Lake of Garda
Bactofugation and the Bactotherm process
The effects of prefrontal lobotomy on aggressive behavior in dogs
Visual rating scales for screening whorl-stage corn for resistance to fall armyworm
Breakdown of seamounts at the trench axis, viewed from gravity anomaly
Kooken; pennsylvania's toughest cave
Recovery of new dinosaur and other fossils from the Early Cretaceous Arundel Clay facies (Potomac Group) of central Maryland, U.S.A
Zubor horny (Bison bonasus) v prirodnych podmienkach Slovensku
The extended Widal test in the diagnosis of fevers due to Salmonella infection
Hair of the american mastodon indicates an adaptation to a semi aquatic habitat

Effect of dietary fat content in meals on pharmacokinetics of quazepam


Effect of dietary fat content in meals on pharmacokinetics of quazepam



Journal of Clinical Pharmacology 42(12): 1335-1340



ISSN/ISBN: 0091-2700

PMID: 12463728

DOI: 10.1177/0091270002042012004

Dietary fat content in meals has been reported to increase the absorption of several drugs proportionately. However, there is no information about the effects of dietary fat in meals on the sedative hypnotic agent quazepam, although limited data suggest that food intake alters quazepam absorption. Therefore, the authors measured and compared pharmacokinetic parameters of quazepam taken in a fasted state and taken 30 minutes after consuming meals containing different amounts of dietary fat.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 003726673

Download citation: RISBibTeXText

Related references

Liquid chromatographic assay and pharmacokinetics of quazepam and its metabolites following sublingual administration of quazepam. Pharmaceutical Research 5(6): 365-368, 1988

Effect of St Johns Wort on the pharmacokinetics and pharmacodynamics of quazepam. Clinical Pharmacology and Therapeutics 73(2): P44, 2003

Effect of test meals of varying dietary fiber content on plasma insulin and glucose response. American Journal of Clinical Nutrition 34(3): 328-334, 1981

Selective affinity of the benzodiazepines quazepam and 2-oxo-quazepam for BZ1 binding site and demonstration of 3H-2-oxo-quazepam as a BZ1 selective radioligand. Life Sciences 42(2): 179-187, 1988

Effect of different timing of meals in the dietary treatment of obesity single daily meal vs. 3 low calorie meals. Melchionda, N , D L Horwitz And D S Schade (Ed ) Serono Symposia Publications Fron Raven Press, Vol 8 Recent Advances in Obesity And Diabetes Research Xxviii+414p Raven Press: New York, N Y , Usa Illus P201-204, 1984

Content of dietary fibre in ready to eat meals. Ernahrung 24(5): 210-213, 2000

Dietary salt and the glycaemic response to meals of different fibre content. European Journal of Clinical Nutrition 43(10): 699-703, 1989

Effects of foods on the pharmacokinetics and clinical efficacy of quazepam. Nihon Shinkei Seishin Yakurigaku Zasshi 23(5): 205-210, 2003

Evaluation of the content and composition of dietary fiber in daily meals of children. Roczniki Panstwowego Zakladu Higieny 36(3): 235-241, 1985

Process for increasing soluble dietary fiber content of soybean meals. Transactions of the Chinese Society of Agricultural Engineering 23(5): 246-250, 2007

Time effects of food intake on the pharmacokinetics and pharmacodynamics of quazepam. British Journal of Clinical Pharmacology 55(4): 382-388, 2003

Single oral dose pharmacokinetics of quazepam is influenced by CYP2C19 activity. Therapeutic Drug Monitoring 26(5): 529-533, 2004

Different effects of light food on pharmacokinetics and pharmacodynamics of three benzodiazepines, quazepam, nitrazepam and diazepam. Journal of Clinical Pharmacy and Therapeutics 32(1): 31-39, 2007

Longitudinal study on pharmacodynamics and pharmacokinetics of acute, steady-state and withdrawn quazepam. Arzneimittel-Forschung 39(2): 276-283, 1989

Effect of low-, moderate-, and high-fat meals on raltegravir pharmacokinetics. Journal of Clinical Pharmacology 51(3): 422-427, 2011