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Effect of dietary fat content in meals on pharmacokinetics of quazepam

Effect of dietary fat content in meals on pharmacokinetics of quazepam

Journal of Clinical Pharmacology 42(12): 1335-1340

ISSN/ISBN: 0091-2700

PMID: 12463728

DOI: 10.1177/0091270002042012004

Dietary fat content in meals has been reported to increase the absorption of several drugs proportionately. However, there is no information about the effects of dietary fat in meals on the sedative hypnotic agent quazepam, although limited data suggest that food intake alters quazepam absorption. Therefore, the authors measured and compared pharmacokinetic parameters of quazepam taken in a fasted state and taken 30 minutes after consuming meals containing different amounts of dietary fat.

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Accession: 003726673

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