Aviation Space and Environmental Medicine 74(1): 37-46
2003
ISSN/ISBN: 0095-6562
PMID: 12546297
Background: A negative fluid balance during bed rest (BR) is accompanied by decreased plasma volume (PV) which contributes to cardiovascular deconditioning. Hypothesis: We hypothesized that increasing dietary sodium while controlling fluid intake would increase plasma osmolality (Posm), stimulate fluid conserving hormones, and reduce fluid/electrolyte (F/E) losses during BR; conversely, decreasing dietary sodium would decrease Posm, suppress fluid conserving hormones, and increase F/E losses.