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Effect of estrogen treatment and vitamin D status on differing bioavailabilities of calcium carbonate and calcium citrate

Effect of estrogen treatment and vitamin D status on differing bioavailabilities of calcium carbonate and calcium citrate

Journal of Clinical Pharmacology 42(11): 1251-1256

The authors hypothesized that estrogen treatment or vitamin D status may affect the bioavailability of two common calcium supplements differently. Using data derived from a recent trial in 25 postmenopausal women, the authors found that Delta AUC of serum calcium after subtraction of placebo was significantly higher after calcium citrate (median, 0.85; 25th to 75th percentile, 0.70 to 3.15) than after calcium carbonate (0.25; -0.58 to 1.00) in non-estrogen-treated patients.

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Accession: 003727868

Download citation: RISBibTeXText

PMID: 12412824

DOI: 10.1177/009127002762491343

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