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Effect of exogenous interleukin-18 (IL-18) and IL-12 in the course of Brucella abortus 2308 infection in mice



Effect of exogenous interleukin-18 (IL-18) and IL-12 in the course of Brucella abortus 2308 infection in mice



Clinical and Diagnostic Laboratory Immunology 9(2): 491-492



In this study we demonstrated that combined inoculation of interleukin-12 (IL-12) and IL-18 reduced the number of bacteria in the spleens of mice infected with Brucella abortus 2308 and that the effect of the treatment was mediated by an increased capability of spleen cells to produce gamma interferon at the early phase of infection.

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Accession: 003727963

Download citation: RISBibTeXText

PMID: 11874900

DOI: 10.1128/CDLI.9.2.491-492.2002



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