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Effect of oral iron supplementation on oxidative stress and colonic inflammation in rats with induced colitis



Effect of oral iron supplementation on oxidative stress and colonic inflammation in rats with induced colitis



Alimentary Pharmacology and Therapeutics 15(12): 1989-1999



Background: Iron supplementation may increase disease activity in ulcerative colitis, possibly through the production of reactive oxygen species from the Fenton reaction. Aim: To assess the effects of two doses of oral iron on intestinal inflammation and oxidative stress in experimental colitis. Methods: Colitis was induced in rats by giving 5% dextran sulfate sodium in drinking water for 7 days.

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Accession: 003731987

Download citation: RISBibTeXText

PMID: 11736731

DOI: 10.1046/j.1365-2036.2001.01113.x



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