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Enhanced uptake of modified low-density lipoprotein by eicosapentaenoic acid-treated THP-1 macrophages

Enhanced uptake of modified low-density lipoprotein by eicosapentaenoic acid-treated THP-1 macrophages

Nutritional Sciences 4(1): 26-33

Animal and clinical studies as well as epidemiological data have provided convincing evidence that n-3 polyunsaturated fatty acids can protect against atherosclerosis. However, the effects of the fatty acids on atherogenesis are contradictory. This discrepancy could derive from great susceptibility of the fatty acids to oxidation. We investigated the effect of eicosapentaenoic acid (EPA) on cellular atherogenesis via the scavenger receptor of THP-1 derived macrophages.

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Accession: 003751263

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