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Evaluation of separation quality in two-dimensional hyphenated chromatography



Evaluation of separation quality in two-dimensional hyphenated chromatography



Analytica Chimica Acta 450(1/2): 99-114



In this paper, a novel criterion named the overlap index (OVI) has been proposed to evaluate the separation quality in two-dimensional hyphenated chromatography. This criterion, which is obtained from the maximum value of the Gram determinant constructed by the key spectra, can reveal the degree of two-dimensional hyphenated chromatographic separation. The key spectra are selected based on the so-called D-optimal criterion.

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Accession: 003760287

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DOI: 10.1016/s0003-2670(01)01368-x


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