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Chapter 3,766

Expression and regulation of cytosolic prostaglandin E synthase in mouse uterus during the peri-implantation period

Ni, H.; Sun, T.; Ma, X-Hong.; Yang, Z-Ming.

Biology of Reproduction 68(3): 744-750

2003

ISSN/ISBN: 0006-3363
PMID: 12604621
DOI: 10.1095/biolreprod.102.007328
Accession: 003765087
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Prostaglandin E2 (PGE2) is considered important for blastocyst spacing, implantation and decidualization in rodent uteri. PGE synthase (PGES) catalyses the isomerization of PGH2 to PGE2. Two isoforms of PGES exist: microsomal PGES (mPGES) and cytosolic PGES (cPGES); however, the expression and regulation of cPGES in the mammalian uterus during early pregnancy are still unknown.

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