Flow cytometry antifungal susceptibility testing of Aspergillus fumigatus and comparison of mode of action of voriconazole vis-à-vis amphotericin B and itraconazole
Ramani, R.; Gangwar, M.; Chaturvedi, V.
Antimicrobial Agents and Chemotherapy 47(11): 3627-3629
2003
ISSN/ISBN: 0066-4804 PMID: 14576132 DOI: 10.1128/aac.47.11.3627-3629.2003
Accession: 003773652
Aspergillus fumigatus isolates were tested with three antifungals by flow cytometry (FC) and fluorescence-activated cell sorting. FC results after 4 h correlated well with MICs obtained by the NCCLS M38-A method; voriconazole exhibited fungicidal activity, albeit to a lesser extent than amphotericin B, but to a greater extent than itraconazole.
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