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Intrinsic signals in the sexually dimorphic circulating growth hormone profiles of the rat



Intrinsic signals in the sexually dimorphic circulating growth hormone profiles of the rat



Molecular and Cellular Endocrinology 173(1/2): 167-181



Male rats secrete growth hormone (GH) in episodic bursts every 3.5-4 h. Between the peaks, GH levels are undetectable. In females, GH secretory profiles are characterized as continuous because hormone concentrations are always measurable in the circulation. These gender differences in the circulating GH profiles are responsible, to varying degrees, for observed sexual dimorphisms ranging from body growth to the expression of hepatic cytochrome P-450 (P-450, CYP) isoforms.

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Accession: 003822885

Download citation: RISBibTeXText

PMID: 11223188

DOI: 10.1016/s0303-7207(00)00401-9


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