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Preliminary observations on the experimental transmission of scrapie to elk (Cervus elaphus nelsoni) by intracerebral inoculation

Hamir, A.N.; Miller, J.M.; Cutlip, R.C.; Stack, M.J.; Chaplin, M.J.; Jenny, A.L.

Veterinary Pathology 40(1): 81-85

2003

ISSN/ISBN: 0300-9858
PMID: 12627716
DOI: 10.1354/vp.40-1-81
Accession: 003893449
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To determine the transmissibility of scrapie to Rocky Mountain elk (Cervus elaphus nelsoni), six elk calves were inoculated intracerebrally with brain suspension from sheep naturally affected with scrapie. One elk developed a brain abscess and was euthanatized at 7 weeks postinoculation (PI), and two others died at 6 and 15 months PI because of physical injuries. At 25 and 35 months PI, two other elk died after brief terminal neurologic episodes.

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Related References

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