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Role of Th1/Th2 immune deviation mediated by nitric oxide in granuloma formation of mice infected with Schistosoma japonicum


Role of Th1/Th2 immune deviation mediated by nitric oxide in granuloma formation of mice infected with Schistosoma japonicum



Chinese Journal of Zoonoses 18(5): 29-32



A study was conducted to investigate the dynamics of liver granuloma and the relative changes of nitric oxide and Th1/Th2 cytokine levels in mice infected with Schistosoma japonicum and probe the role of NO in granuloma formation as a mediator of Th1/Th2 immune deviation. The livers of infected mice were examined histologically. Tissue sections were HE-stained and the size of granuloma was assessed microscopically.

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