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Studies using the estrogen receptor alpha knockout uterus demonstrate that implantation but not decidualization-associated signaling is estrogen dependent



Studies using the estrogen receptor alpha knockout uterus demonstrate that implantation but not decidualization-associated signaling is estrogen dependent



Biology of Reproduction 67(4): 1268-1277



Ovarian hormonal signalling is essential for proper functioning of the uterus in the establishment of pregnancy. Previous studies have demonstrated that decidualization, a stromal transformation that occurs in response to embryo implantation, can be elicited in the uterus of oestrogen receptor alpha knockout ( alpha ERKO) mice in the absence of the oestrogen dependence normally seen in wild-type (WT) mice for this response.

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Accession: 003949603

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PMID: 12297545


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Studies Using the Estrogen Receptor Knockout Uterus Demonstrate That Implantation but Not Decidualization-Associated Signaling Is Estrogen Dependent. Biology of Reproduction 67(4): 1268-1277, 2002

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