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Susceptibility to aflatoxin B1-related primary hepatocellular carcinoma in mice and humans

Susceptibility to aflatoxin B1-related primary hepatocellular carcinoma in mice and humans

Cancer Research 63(15): 4594-4601

The genetic basis of disease susceptibility can be studied by several means, including research on animal models and epidemiological investigations in humans. The two methods are infrequently used simultaneously, but their joint use may overcome the disadvantages of either method alone. We used both approaches in an attempt to understand the genetic basis of aflatoxin B1 (AFB1)-related susceptibility to hepatocellular carcinoma (HCC).

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Accession: 003955489

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PMID: 12907637

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