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Ultrastructural pathologic observation on the gut-associated lymphoid tissues of sacculus rotundus of rabbits infected with rabbit haemorrhagic disease virus



Ultrastructural pathologic observation on the gut-associated lymphoid tissues of sacculus rotundus of rabbits infected with rabbit haemorrhagic disease virus



Agricultural Sciences in China 2(4): 446-453



A total of 12 New Zealand white rabbits infected with rabbit haemorrhagic disease virus (RHDV) and 4 healthy rabbits (control) were studied. Rabbits infected with RHDV showed varying degrees of lesions. There were numerous holes at the luminal and basement membrane surfaces of the dome epithelium (DE), consistently accompanied by necrosis of lymphocytes and M-cells, and pronounced depletion of lymphocytes in the domes and follicles.

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Accession: 003996590

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