+ Site Statistics
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

Antidiabetic effect of Cinnamomum cassia and Cinnamomum zeylanicum in vivo and in vitro

Antidiabetic effect of Cinnamomum cassia and Cinnamomum zeylanicum in vivo and in vitro

PhytoTherapy Research 19(3): 203-206

Rats were given Cinnamomum cassia bark or extracts from Cinnamomum cassia and zeylanicum to evaluate blood glucose and plasma insulin levels in rats under various conditions. The cassia extract was superior to the zeylanicum extract. The cassia extract was slightly more efficacious than the equivalent amount of Cassia bark. A decrease in blood glucose levels was observed in a glucose tolerance test (GTT), whereas it was not obvious in rats that were not challenged by a glucose load. The elevation in plasma insulin was direct since a stimulatory in vitro effect of insulin release from INS-1 cells (an insulin secreting cell line) was observed. Thus the cassia extract has a direct antidiabetic potency.

(PDF emailed within 0-6 h: $19.90)

Accession: 004042360

Download citation: RISBibTeXText

PMID: 15934022

DOI: 10.1002/ptr.1643

Related references

Studies on the inner morphology of lauraceae part 1 on the bark of cinnamomum burmanni cinnamomum cassia cinnamomum zeylanicum and cinnamomum iners. Acta Phytotaxonomica et Geobotanica 26(3-4): 96-106, 1974

Salmonella and fecal coliforms in cinnamon (Cinnamomum cassia Blume and Cinnamomum zeylanicum Nees) sold in the city of Florian polis, Santa Catarina, Brazil. Cadernos de Saude Publica 11(4): 624-628, 1995

Studies on Cinnamomum zeylanicum. I. The essential oil components of Cinnamomum zeylanicum Nees grown in Ghana. Planta medica: 21 (4) 416-420, 1972

Differentiation of some essential oils with similar composition particularly by uv ir and raman spectra part 4 essential oil of ceylon cinnamon cinnamomum zeylanicum and of china cinnamon cinnamomum cassia. Plantes Medicinales et Phytotherapie 6(1): 11-19, 1972

Immuno pharmacological studies of the aqueous extract of cinnamomum cassia 2. effect of cinnamomum cassia aqueous extract on experimental glomerulo nephritis. Japanese Journal of Pharmacology 32(5): 823-832, 1982

Stomatogenesis in cinnamomum camphora and cinnamomum zeylanicum. Acta Botanica Indica 6(SUPPL): 171-173, 1978

Tannins and related compounds xxxix. procyanidin c glucosides and an acylated flavan 3 ol glucoside from the barks of cinnamomum cassia and cinnamomum obtusifolium. Chemical and Pharmaceutical Bulletin 34(2): 643-649, 1986

Tannins and related compounds 29. 7 new methyl derivatives of flavan 3 ols and a 1 3 diarylpropan 2 ol from cinnamomum cassia cinnamomum obtusifolium and lindera umbellata var membranacea. Chemical and Pharmaceutical Bulletin 33(6): 2281-2286, 1985

Anti-Inflammatory Activities of Cinnamomum cassia Constituents In Vitro and In Vivo. Evidence-Based Complementary and Alternative Medicine 2012: 429320, 2012

In Vitro Effect of Cinnamomum zeylanicum Blume Essential Oil on Candida spp. Involved in Oral Infections. Evidence-Based Complementary and Alternative Medicine 2018: 4045013, 2018

INHIBITORY EFFECT in vitro OF EXTRACTS Cinnamomum zeylanicum BLUME IN CONTROL OF Cylindrocladium candelabrum. Ciencia Florestal 28(4): 1559-1567, 2018

Verification of the antidiabetic effects of cinnamon (Cinnamomum zeylanicum) using insulin-uncontrolled type 1 diabetic rats and cultured adipocytes. Bioscience, Biotechnology, and Biochemistry 74(12): 2418-2425, 2011

Cinnamomum cassia exhibits antileishmanial activity against Leishmania donovani infection in vitro and in vivo. Plos Neglected Tropical Diseases 13(5): E0007227, 2019

In vitro and in vivo safety studies of cinnamon extract (Cinnamomum cassia) on general and genetic toxicology. Regulatory Toxicology and Pharmacology 95: 115-123, 2018

The essential oil from the twigs of Cinnamomum cassia Presl inhibits oxytocin-induced uterine contraction in vitro and in vivo. Journal of Ethnopharmacology 206: 107-114, 2017