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Characterization of monoclonal antibody against SARS coronavirus nucleocapsid antigen and development of an antigen capture ELISA



Characterization of monoclonal antibody against SARS coronavirus nucleocapsid antigen and development of an antigen capture ELISA



Journal of Virological Methods 127(1): 46-53



This report describes the production of several MAbs against N195 protein, a major immunodomain of SARS CoV nucleocapsid protein (He, Q., Chong, K.H., Chang, H.H., Leung, B., Ling, A.E., Wei, T., Chan, S.W., Ooi, E.E., Kwang, J., 2004. Development of a Western blot assay for detection of antibodies against coronavirus causing severe acute respiratory syndrome. Clin. Diagn. Lab. Immunol. 11 (2) 417-422.). One representative IgG1 monoclonal antibody (MAb), S-A5D5, was selected and characterized.

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Accession: 004070743

Download citation: RISBibTeXText

PMID: 15893565

DOI: 10.1016/j.jviromet.2005.03.004


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