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Comparison of antigenicity between expressed proteins of the fragment including S gene whole antigenic sites and the deleted fragment in porcine respiratory coronavirus of transmissible gastroenteritis virus



Comparison of antigenicity between expressed proteins of the fragment including S gene whole antigenic sites and the deleted fragment in porcine respiratory coronavirus of transmissible gastroenteritis virus



Chinese Journal of Virology 21(5): 384-388



Porcine respiratory coronavirus (PRCV) is a deletion mutant of transmissible gastroenteritis virus (TGEV) with altered respiratory tissue tropism. The important difference between them is that PRCV has a large deletion of two antigenic sites, B and C, in the 5' region of the S gene. Two pairs of oligonucleotide primers appropriate for PCR amplification were designed based on the gene encoding the S protein of TGEV.

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Accession: 004081700

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