+ Site Statistics
References:
54,258,434
Abstracts:
29,560,870
PMIDs:
28,072,757
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

Complete mass balance of dietary polychlorinated dibenzo-p-dioxins and dibenzofurans in dairy cattle and characterization of the apparent synthesis of hepta- and octachlorodioxins



Complete mass balance of dietary polychlorinated dibenzo-p-dioxins and dibenzofurans in dairy cattle and characterization of the apparent synthesis of hepta- and octachlorodioxins



Journal of Agricultural and Food Chemistry 50(15): 4226-4231



Mass balances of 2,3,7,8-substituted dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs) were measured in cows following administration of pentachlorophenol (PCP)-treated wood. Fecal excretion accounted for the major fraction of all congeners. Recovery in feces increased with increasing chlorination, while storage in body fat and excretion in milk decreased with increasing chlorination. The PCDFs with no chlorines in the 4- and 6-positions were apparently metabolized because residues were not detected in milk and body fat. Storage and excretion of 1,2,3,4,6,7,8-HpCDD and 1,2,3,4,6,7,8,9-OCDD exceeded intake by factors of 1.7 and 3.4, but recovery of other PCDD/Fs did not exceed intake significantly. Excess excretion of OCDD, but not HpCDD, was confirmed in a follow-up study. Synthesis of HpCDD and OCDD did not occur when PCP-treated wood was fermented with rumen microorganisms, and enhanced concentrations of HpCDD and OCDD were not found in gastrointestinal tract contents of dosed animals. Formation of OCDD during incubation of feces spiked with PCP-treated wood led to the conclusion that synthesis was postexcretion during sample preparation.

(PDF emailed within 1 workday: $29.90)

Accession: 004084314

Download citation: RISBibTeXText

PMID: 12105950


Related references

Complete Mass Balance of Dietary Polychlorinated Dibenzo- p -dioxins and Dibenzofurans in Dairy Cattle and Characterization of the Apparent Synthesis of Hepta- and Octachlorodioxins. Journal of Agricultural and Food Chemistry 50(15): 4226-4231, 2002

Retention and maternal transfer of environmentally relevant polybrominated dibenzo-p-dioxins and dibenzofurans, polychlorinated dibenzo-p-dioxins and dibenzofurans, and polychlorinated biphenyls in zebrafish (Danio rerio) after dietary exposure. Environmental Toxicology and Chemistry 31(4): 804-812, 2012

Global mass balance for polychlorinated dibenzo-p-dioxins and dibenzofurans. Environmental Science & Technology. 30(6): 1797-1804, 1996

Chlorinated dioxins and dibenzofurans in Ontario - analysing and controlling the risks: Development of scientific criteria document leading to multi-media standards for polychlorinated dibenzo-p-dioxins (PCDDs) and dibenzo polychlorinated dibenzofurans (PCDFs). Chemosphere 15(9-12): 1835-1850, 1986

Comment on Global mass balance for polychlorinated dibenzo-p-dioxins and dibenzofurans. Environmental Science and Technology 30: 46-8, 1996

Apportionment of sources of polychlorinated dibenzo-P-dioxins and dibenzofurans by a chemical mass balance model. Water Research. 31(12): 2935-2948,., 1997

Is Combustion the Major Source of Polychlorinated Dibenzo- p -dioxins and Dibenzofurans to the Environment? A Mass Balance Investigation. Environmental Science & Technology 34(14): 2879-2886, 2000

Is combustion the major source of polychlorinated dibenzo-p-dioxins and dibenzofurans to the environment? A mass balance investigation. Environmental Science & Technology 34(14): 2879-2886, July 15, 2000

Influence of the large grid size used in a multimedia mass balance model (POPsME) on the exposure assessment of polychlorinated dibenzo-p-dioxins and dibenzofurans. Environmental Science & Technology 41(15): 5231-5236, 2007

Influence of the Large Grid Size Used in a Multimedia Mass Balance Model (PopsMe) on the Exposure Assessment of Polychlorinated Dibenzo- p -dioxins and Dibenzofurans. Environmental Science & Technology 41(15): 5231-5236, 2007

Dietary exposure and risk assessment of polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans and dioxin-like polychlorinated biphenyls of the population in the Region of Valencia (Spain). Food Additives and Contaminants. Part A, Chemistry, Analysis, Control, Exposure and Risk Assessment 35(4): 740-749, 2017

A survey of dietary intake of polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans, and dioxin-like coplanar polychlorinated biphenyls from food during 2000-2002 in Osaka City, Japan. Archives of Environmental Contamination and Toxicology 60(3): 543-555, 2011

Thermodynamic prediction of vapor pressures for polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans, and polybrominated dibenzo-p-dioxins. Environmental Toxicology and Chemistry 24(9): 2167-2177, 2005

Dietary intakes of polychlorinated dibenzo-p-dioxins, dibenzofurans and polychlorinated biphenyls in Finland. Food Additives and Contaminants 18(11): 945-953, 2001

Human dietary exposure to polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans in Taiwan. Journal of Hazardous Materials 164(2-3): 621-626, 2008