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Compliance with 14-day primaquine therapy for radical cure of vivax malaria - a randomized placebo-controlled trial comparing unsupervised with supervised treatment



Compliance with 14-day primaquine therapy for radical cure of vivax malaria - a randomized placebo-controlled trial comparing unsupervised with supervised treatment



Transactions of the Royal Society of Tropical Medicine and Hygiene 98(3): 168-173



The only available treatment that can eliminate the latent hypnozoite reservoir of vivax malaria is a 14-day course of primaquine (PQ). A potential problem with long-course chemotherapy is the issue of compliance after clinical symptoms have subsided. The present study, carried out at an Afghan refugee camp in Pakistan, between June 2000 and August 2001, compared 14-day treatment in supervised and unsupervised groups in which compliance was monitored by comparison of relapse rates.

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Accession: 004084472

Download citation: RISBibTeXText

PMID: 15024927

DOI: 10.1016/s0035-9203(03)00041-5


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