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Contact dermatitis associated with Astronium urundeuva (allemao) Engl., a traditional medicinal plant from Brazil



Contact dermatitis associated with Astronium urundeuva (allemao) Engl., a traditional medicinal plant from Brazil



Contact Dermatitis 51(5/6): 311



Extracts of Astronium urundeuva, a northeastern Brazilian folk medicine, were used in patch tests to determine prevalence of sensitivity and the dominant allergens involved with sensitization. A transverse study of cases of contact dermatitis and sensitization to A. urundeuva was performed on 137 patients attending the Dermatology Center of Walter Cantidio University Hospital/Federal University of Ceara in Brazil. The patients were submitted to patch test using hexane and ethanol extract of A. urundeuva and derived fractions. The patch testing was preceded by anamnese and physical examination then applied using: standard series, hexane and ethanol extracts at 2.5, 5.0 and 10.0%; fractions of the hexane (Aur1, Aur2) and ethanol extracts (Aur3, Aur4) at 1.0 and 2.0% and cardol at 1.0% concentrations. Three of 137 (2%) patients showed one or more positive reactions to the hexane and ethanol extracts and fractions of A. urundeuva in the patch tests. Patient 1 had a positive test to 5.0 and 10.0% EtOH extract. He reported using topical preparation of A. urundeuva to treat a cutaneous rash, but instead of improvement, had accentuation of the lesions. Lesions resolved once treatment with the A. urundeuva preparation was stopped. Patient 2 showed positive results for the hexane extract, fraction Aur4 (2%) and cardol (1%). The patient also reported an improvement of the dermatitis, after suspension of topical use of A. urundeuva. Patient 3 had positive results with the fractions Aur3 (1%) and Aur4 (2%).

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Accession: 004087412

Download citation: RISBibTeXText

PMID: 15606659

DOI: 10.1111/j.0105-1873.2004.0459a.x


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