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Cytotoxic activity of methanol extracts from Basidiomycete mushrooms on murine cancer cell lines



Cytotoxic activity of methanol extracts from Basidiomycete mushrooms on murine cancer cell lines



Die Pharmazie 59(4): 290-293



Crude methanol extracts of 58 mushroom species were screened for their cytotoxic activities against 2 murine cancer cell lines, L1210 and 3LL, using the tetrazolium assay. A majority of the extracts (74%) exhibited IC50>100 micro g/ml against both cell lines. The most marked activity against 1 of the cell lines was noted for 9 species (14% of the tested species). While Amanitales and Russulales species evaluated were not active, Polyporales and Boletales gave better results.

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Accession: 004094284

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PMID: 15125575


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