Effect of acetic acid present in bagasse hydrolysate on the activities of xylose reductase and xylitol dehydrogenase in Candida guilliermondii
Lima, L.Helena.Augusto.; das Graças de Almeida Felipe, M.; Vitolo, M.; Torres, F.Araripe.Gonçalves.
Applied Microbiology and Biotechnology 65(6): 734-738
ISSN/ISBN: 0175-7598 PMID: 15107950 DOI: 10.1007/s00253-004-1612-8
The first two steps in xylose metabolism are catalyzed by NAD(P)H-dependent xylose reductase (XR) (EC 220.127.116.11) and NAD(P)-dependent xylitol dehydrogenase (XDH) (EC 18.104.22.168), which lead to xylose->xylitol->xylulose conversion. Xylitol has high commercial value, due to its sweetening and anticariogenic properties, as well as several clinical applications.