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Chapter 4,151

Evaluation of a West Nile virus immunoglobulin a capture enzyme-linked immunosorbent assay

Prince, H.E.; Lapé-Nixon, M.

Clinical and Diagnostic Laboratory Immunology 12(1): 231-233

2005


ISSN/ISBN: 1071-412X
PMID: 15643014
DOI: 10.1128/cdli.12.1.231-233.2005
Accession: 004150022

An in-house-developed enzyme-linked immunosorbent assay detected West Nile virus (WNV) immunoglobulin A (IgA) in 65 of 68 sera from WNV-infected patients; 40 of 63 WNV IgM-positive, IgG-negative serum or plasma specimens; 65 of 67 WNV IgM-positive, IgG-positive specimens; 0 of 70 WNV IgM-negative, IgG-negative specimens; and 0 of 64 archived blood donation sera. WNV IgA is thus highly prevalent among WNV-infected patients and typically appears after WNV IgM but before WNV IgG.

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