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Human flora-associated (HFA) animals as a model for studying the role of intestinal flora in human health and disease



Human flora-associated (HFA) animals as a model for studying the role of intestinal flora in human health and disease



Current Issues in Intestinal Microbiology 6(2): 69-75



Although the intestinal flora in animals plays an important role in health and disease, there is little direct information regarding the role of the human intestinal flora. By inoculating germfree animals with human faeces, the major components of the human flora can be transferred into the ex-germfree animals, i.e. human flora-associated (HFA) animals. HFA animals therefore provide a stable model for studying the ecosystem and metabolism of the human intestinal flora.

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Accession: 004188346

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PMID: 16107039


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