Section 5
Chapter 4,286

Proliferative responses to canine thyroglobulin of peripheral blood mononuclear cells from hypothyroid dogs

Tani, H.; Nabetani, T.; Sasai, K.; Baba, E.

Journal of Veterinary Medical Science 67(4): 363-368


ISSN/ISBN: 0916-7250
PMID: 15876785
DOI: 10.1292/jvms.67.363
Accession: 004285393

The immune responses of hypothyroid dogs to canine thyroglobulin (cTg) were evaluated for the proliferative ability of peripheral blood mononuclear cells (PBMC). PBMC from three hypothyroid dogs with high titers of thyroglobulin autoantibody (TgAA) and 3 clinically normal dogs were cultured with 5, 10, or 20 micro g/ml of cTg for 72 hr. The proliferative responses of the cells were determined by the level of incorporated BrdU.

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