+ Site Statistics
References:
54,258,434
Abstracts:
29,560,870
PMIDs:
28,072,757
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Quantitative trait loci affecting dengue midgut infection barriers in an advanced intercross line of Aedes aegypti



Quantitative trait loci affecting dengue midgut infection barriers in an advanced intercross line of Aedes aegypti



Insect Molecular Biology 13(6): 637-648



Quantitative trait loci (QTL) affecting the ability of the Aedes aegypti midgut to become infected with Dengue 2 virus (DEN2) were mapped in the F5 generation of an advanced intercross line (AIL). A strain of Ae. aegypti previously selected for DEN2 susceptibility was crossed to a new strain selected for refractoriness to midgut infection. In P1 and F1 parents and 147 F5 offspring, genotypes at forty-four cDNA loci were analysed. A new sex linked QTL and a second QTL on chromosome II with genotypes subject to balancing selection were detected that condition midgut susceptibility. Alleles at these QTL contributed additively in determining susceptibility and accounted for approximately 24% of the phenotypic variance. Markers associated with a midgut escape barrier were inconsistently supported.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 004290762

Download citation: RISBibTeXText

PMID: 15606812

DOI: 10.1111/j.0962-1075.2004.00522.x


Related references

An advanced intercross line resolves Eae18 into two narrow quantitative trait loci syntenic to multiple sclerosis candidate loci. Journal of Immunology 173(2): 1366-1373, 2004

Quantitative trait loci that control dengue-2 virus dissemination in the mosquito Aedes aegypti. Genetics 170(1): 185-194, 2005

Quantitative trait loci that control vector competence for dengue-2 virus in the mosquito Aedes aegypti. Genetics 156(2): 687-698, 2000

Fine mapping of collagen-induced arthritis quantitative trait loci in an advanced intercross line. Journal of Immunology 177(10): 7042-7049, 2006

Using an advanced intercross line to identify quantitative trait loci controlling immune response during collagen-induced arthritis. Genes and Immunity 8(4): 296-301, 2007

Quantitative trait loci identified for blood chemistry components of an advanced intercross line of chickens under heat stress. Bmc Genomics 17: 287, 2016

Use of an advanced intercross line population for precise mapping of quantitative trait loci for gray leaf spot resistance in maize. Crop Science: 5, 1696-1704, 2008

Quantitative trait loci for energy balance traits in an advanced intercross line derived from mice divergently selected for heat loss. Peerj 2: E392, 2014

Quantitative Trait Loci Affecting Rous Sarcoma Virus Induced Tumor Regression Trait in F2 Intercross Chickens. Asian-Australasian Journal of Animal Sciences 22(10): 1359-1365, 2009

Identification of quantitative trait loci for body temperature, body weight, breast yield, and digestibility in an advanced intercross line of chickens under heat stress. Genetics, Selection, Evolution 47: 96, 2016

Identification of quantitative trait loci affecting body composition in a mouse intercross. Proceedings of the National Academy of Sciences of the United States of America 103(52): 19860-5, 2006

Quantitative trait loci affecting the behavior of A/J and CBA/J intercross mice in the elevated plus maze. Mammalian Genome 12(7): 501-507, 2001

Mapping resolution of quantitative trait loci in advanced intercross generations. Proceedings, 5th World Congress on Genetics Applied to Livestock Production, University of Guelph, Guelph, Ontario, Canada, 7-12 August 1994 Volume 21 Gene mapping; polymorphisms; disease genetic markers; marker assisted selection; gene expression; transgenes; non conventional animal products; conservation genetics; conservation of domestic animal genetic resources: 21-24, 1994

Genetic mapping of quantitative trait loci affecting growth and carcass traits in F2 intercross chickens. Poultry Science 88(3): 477-482, 2009

Using advanced intercross lines for high-resolution mapping of HDL cholesterol quantitative trait loci. Genome Research 13(7): 1654-1664, 2003