EurekaMag.com logo
+ Site Statistics
References:
53,869,633
Abstracts:
29,686,251
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on LinkedInFollow on LinkedIn

+ Translate

Systemic iron supplementation replenishes iron stores without enhancing colon carcinogenesis in murine models of ulcerative colitis: comparison with iron-enriched diet



Systemic iron supplementation replenishes iron stores without enhancing colon carcinogenesis in murine models of ulcerative colitis: comparison with iron-enriched diet



Digestive Diseases and Sciences 50(4): 696-707



Ulcerative colitis (UC) patients frequently require iron supplementation to remedy anemia. The impact of systemic iron supplementation (intraperitoneal injection) on UC-associated carcinogenesis was assessed in mice subjected to cyclic dextran sulfate sodium (DSS) treatment and compared with dietary iron enrichment. Systemic iron supplementation, but not a twofold iron diet, remedied iron deficiency as indicated by the histochemical detection of splenic iron stores.

(PDF emailed within 0-6 h: $19.90)

Accession: 004339831

Download citation: RISBibTeXText

PMID: 15844705

DOI: 10.1007/s10620-005-2560-6



Related references

The switch to an iron deficient diet elicits changes in intestinal iron absorption and the expression of iron transport molecules without changes in body iron stores. Gastroenterology 122(4 Suppl 1): A 39, April, 2002

A comparison of the plasma iron, iron-binding capacity, sternal marrow iron and other methods in the clinical evaluation of iron, stores. Annals of Internal Medicine 48(1): 60-82, 1958

Iron status in Danish women, 1984-1994: a cohort comparison of changes in iron stores and the prevalence of iron deficiency and iron overload. European Journal of Haematology 71(1): 51-61, 2003

Iron status in Danish men 1984-94: a cohort comparison of changes in iron stores and the prevalence of iron deficiency and iron overload. European Journal of Haematology 68(6): 332-340, 2002

High-iron diet: foe or feat in ulcerative colitis and ulcerative colitis-associated carcinogenesis. Journal of Clinical Gastroenterology 40(5): 391-397, 2006

A model of ulcerative colitis-associated carcinogenesis by supplementation of iron in mice. Proceedings of the American Association for Cancer Research Annual Meeting 40: 59, March, 1999

Body iron stores and iron restoration rate in Japanese patients with chronic hepatitis C as measured during therapeutic iron removal revealed neither increased body iron stores nor effects of C282Y and H63D mutations on iron indices. Nagoya Journal of Medical Science 64(1-2): 51-57, 2001

Prevalence of iron deficiency states and risk of haemoconcentration during pregnancy according to initial iron stores and iron supplementation. Public Health Nutrition 16(8): 1371-1378, 2014

Effect of Intravenous Iron Supplementation on Iron Stores in Non-Anemic Iron-Deficient Patients with Hereditary Hemorrhagic Telangiectasia. Hematology Reports 8(1): 6348-6348, 2016

Effect of iron supplementation on iron stores and total body iron after whole blood donation. Transfusion 56(8): 2005-2012, 2017

Iron absorption from the whole diet. Relation to meal composition, iron requirements and iron stores. European Journal of Clinical Nutrition 49(11): 794-808, 1995

Iron stores and haemoglobin iron deficits in menstruating women. Calculations based on variations in iron requirements and bioavailability of dietary iron. European Journal of Clinical Nutrition 54(8): 650-657, 2000

Iron stores and haemoglobin iron deficits in menstruating women. Calculations based on variations in iron requirements and bioavailability of dietary iron. European Journal of Clinical Nutrition 54(8): 650-657, 2000

Dietary iron bioavailability does not affect liver iron stores in iron-normal or iron-loaded swine. FASEB Journal 11(3): A607, 1997

Models for iron oxo proteins structures and properties of iron ii iron iii zinc ii iron iii and iron ii gallium iii complexes with mu phenoxobis mu carboxylatodimetal cores. Journal of the American Chemical Society 111(16): 6183-6195, 1989