Transmission of sheep scrapie to elk (Cervus elaphus nelsoni) by intracerebral inoculation: final outcome of the experiment
Hamir, A.N.; Miller, J.M.; Cutlip, R.C.; Kunkle, R.A.; Jenny, A.L.; Stack, M.J.; Chaplin, M.J.; Richt, J.A.
Journal of Veterinary Diagnostic Investigation Official Publication of the American Association of Veterinary Laboratory Diagnosticians Inc 16(4): 316-321
ISSN/ISBN: 1040-6387 PMID: 15305743 DOI: 10.1177/104063870401600410
This is a final report of an experimental transmission of sheep scrapie agent by intracerebral inoculation to Rocky Mountain elk (Cervus elaphus nelsoni). It documents results obtained in experimental (n=6) and control (n=2) elk. During the first 2 years postinoculation (PI), 3 animals died or were euthanized because of infection or injuries other than spongiform encephalopathy (SE). In years 3 and 4 PI, 3 other inoculated elk died after brief terminal neurological episodes.