+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

A high dietary iodine increases thyroid iodine stores and iodine concentration in blood serum but has little effect on muscle iodine content in pigs



A high dietary iodine increases thyroid iodine stores and iodine concentration in blood serum but has little effect on muscle iodine content in pigs



Meat Science 72(2): 365-372



There is still iodine deficiency in many populations, which justifies efforts to increase this trace element in food such as milk, eggs and meat by fortifying compound animal feeds with extra iodine. The iodine requirement of growing pigs is in the order of 100-200μg/kg feed (as a supplement) and the effects of this dosage range or higher on pork iodine concentration should be determined including the action of relevant iodine antagonists in feed, e.g., rapeseed. In three experiments on a total of 208 pigs [Pietrain×(Landrace×Large White)] the iodine concentration of meat (m. longissimus) - 71 samples -, blood serum - 100 samples - and of the thyroid - 100 samples - was analysed by intracoupled plasma-MS. In Experiment 1, 4×10 pigs received diets without or with rapeseed cake (0 and 3.2mmol glucosinolates/kg diet) either with 125 or with 250μg iodine/kg. In Experiment 2, the three groups with 46 pigs each were fed high iodine diets (1200μg supplementary iodine/kg) without or with 100 or 150g solvent extracted rapeseed meal/kg diet (0; 0.8 and 1.2mmol glucosinolates/kg). In Experiment 3, 3×10 pigs received either 600μg iodine/kg feed (1) or the 5-fold dosage (600+2400μg iodine/kg diet) administered 7 days (2) or 18 days (3) before slaughtering. The group means of pork iodine content were in the relatively small range from 3 to 16μg/kg, which contrasted to the enormously varying dosage range from 125 to 3000μg iodine/kg diet. There was a certain iodine dosage effect in Experiment 3 when - in comparison to the control - a 3-fold higher meat iodine concentration resulted from a 5-fold higher diet iodine concentration. In Experiment 1 with the low iodine offer, rapeseed cake with glucosinolates decreased the serum iodine level whereas in Experiment 2 this did not happen due to higher iodine fed and lower glucosinolates exposure. The thyroid iodine reflected the dietary iodine better than blood serum iodine and the serum better than muscle. However, in Experiment 2, 1200μg iodine/kg diet produced only half the serum iodine concentration than half as much dietary iodine in Experiment 3 (600μg iodine/kg diet), which may result from rapid elimination of blood iodine and a higher urinary excretion by longer duration of feed withdrawal before blood sampling. The muscle of pigs has to be classified as a low iodine food. Thus, there are no possibilities to concentrate this trace element reproducibly in amounts relevant for human nutrition in pork.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 004391621

Download citation: RISBibTeXText

PMID: 22061566

DOI: 10.1016/j.meatsci.2005.08.017


Related references

Effects of fluorine and fluoridated iodine on the iodine content of the rabbit thyroid (Determination of the organic iodine content of the thyroid, autographies of the pituitary gland. Iodine 131). Bulletin der Schweizerischen Akademie der Medizinischen Wissenschaften 15: 412-422, 1959

Serum thyroglobulin and urinary iodine concentration are the most appropriate indicators of iodine status and thyroid function under conditions of increasing iodine supply in schoolchildren in Benin. Journal of Nutrition 131(10): 2701-2706, 2001

The effect of iodine from iodine-enriched alga Chlorella spp. on the pork iodine content and meat quality in finisher pigs. Acta Veterinaria Brno 81(4): 339-346, 2012

The effect of administration of iodine on the total iodine, inorganic iodine, and thyroxine content of the pathological thyroid gland. Jour Biol Chem 97(1): 303-324, 1932

Studies of blood iodine. 1. Iodine content of blood as a measure of thyroid function. Technique of detection of blood iodine. Ztschr. klin. Med 133: 503-512, 1938

Evaluation of the iodine intake: problems of the iodine/creatinine ratio--comparison with iodine excretion and daily fluctuations of iodine concentration. Experimental and Clinical Endocrinology & Diabetes 106(Suppl. 3): S17-S20, 1998

Studies of blood iodine. 5. Effect of iodine and di-iodptyrosine on blood iodine. Iodine quotient and its significance for endocrine action. Ztschr. klin. Med 133: 532-540, 1938

Dose calculations for iodine 123 iodine 124 iodine 125 and iodine 131 in the thyroid gland of the mouse rat and man and comparison with thyroid function for mice and rats. Physics in Medicine & Biology 26(6): 1035-1054, 1981

Concentration of plasma iodine, thyroid uptake of iodine and goiter in persons weith chronic iodine defficiency. Revista Medica de Chile 101(10): 763-767, 1973

Course of thyroid iodine concentration during treatment of endemic goitre with iodine and a combination of iodine and levothyroxine. Acta Endocrinologica 125(6): 662-667, 1991

Influence of iodine contents in cat food on its consumption, urinary iodine excretion and concentration of thyroid hormones in cat blood serum. Medycyna Weterynaryjna 61(8): 900-903, 2005

Dietary evaluation of a low-iodine diet in Korean thyroid cancer patients preparing for radioactive iodine therapy in an iodine-rich region. Nutrition Research and Practice 10(2): 167-174, 2016

Effect of chronic graded doses of ascorbic acid on radioactive iodine uptake iodine 131 peroxidase enzyme iodinating activity of thyroid and protein bound iodine of blood of guinea pig. Indian Journal of Physiology & Allied Sciences 27(2): 71, 1973

Effect of iodine source and dose on growth and iodine content in tissue and plasma thyroid hormones in fattening pigs. European Journal of Nutrition 51(6): 685-691, 2012

Iodine metabism in the human organism. 2. Blood iodine and urinary iodine excretion after a single intravenous injection of inorganic iodine in hypothyroidism. Deutsch. Arch. f. klin. Med 174: 449-455, 1933