Effect of absorption enhancers on nasal ginsenoside Rg1 delivery and its nasal ciliotoxicity
Chen, X-mei.; Zhu, J-bi.; Sun, W-dong.; Zhang, L-jian.
Yao Xue Xue Bao 41(2): 149-155
2006
ISSN/ISBN: 0513-4870 PMID: 16671546 Accession: 004419129
Aim: The enhancing activity and safety of several absorption enhancers were evaluated as potential nasal absorption enhancers to increase intranasal absorption of ginsenoside Rg1. Methods: Nasal circulatory perfusion test in vivo had been employed to investigate the effect of absorption enhancers for nasal mucosa absorption of ginsenoside Rg1 in rats.