Genetic mutations influencing ovulation rate in sheep
McNatty, K.P.; Juengel, J.L.; Wilson, T.; Galloway, S.M.; Davis, G.H.
Reproduction, Fertility and Development 13(7/8): 549-555
Ovulation rate in mammals is determined by a complex exchange of endocrine signals between the pituitary gland and the ovary, and by paracrine signals within ovarian follicles between the oocyte and its adjacent somatic cells. One approach to identifying factors regulating ovulation rate is to find mutations that influence the target phenotype and, in this context, sheep are proving to be remarkable experimental models.