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Ginsenoside extraction from Panax quinquefolium L. (American ginseng) root by using ultrahigh pressure


Ginsenoside extraction from Panax quinquefolium L. (American ginseng) root by using ultrahigh pressure



Journal of pharmaceutical and biomedical analysis 41(1): 57-63



ISSN/ISBN: 0731-7085

PMID: 16332422

DOI: 10.1016/j.jpba.2005.10.043

A new method of ultrahigh pressure extraction (UPE) was used to extract the ginsenosides from Panax quinquefolium L. (American ginseng) root at room temperature. Several solvents, including water, ethanol, methanol, and n-butanol were used in the UPE. The ginsenosides were quantified by a HPLC equipped with UV-vis detector. The results showed that ethanol is the most efficient solvent among the used ones. Compared with other methods, i.e., Soxhlet extraction, heat reflux extraction, ultrasound-assisted extraction, microwave-assisted extraction, and supercritical CO2 extraction, the UPE has the highest extraction yield in the shortest time. The extraction yield of 0.861% ginsenoside-Rc in 2 min was achieved by the UPE, while the yields of 0.284% and 0.661% were obtained in several hours by supercritical CO2 extraction and the heat reflux extraction, respectively.

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Accession: 004435431

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