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Paracrine signaling through the epithelial estrogen receptor alpha is required for proliferation and morphogenesis in the mammary gland



Paracrine signaling through the epithelial estrogen receptor alpha is required for proliferation and morphogenesis in the mammary gland



Proceedings of the National Academy of Sciences of the United States of America 103(7): 2196-2201



Estradiol is a major regulator of postnatal mammary gland development and thought to exert its effects through estrogen receptor alpha (ER alpha ) expressed in the mammary gland stroma and epithelium. Previous studies, however, were confounded by the use of an ER alpha mutant strain that retains some of the protein with transactivation activity.

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Accession: 004457960

Download citation: RISBibTeXText

PMID: 16452162

DOI: 10.1073/pnas.0510974103



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