+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Soy phytochemicals prevent orthotopic growth and metastasis of bladder cancer in mice by alterations of cancer cell proliferation and apoptosis and tumor angiogenesis



Soy phytochemicals prevent orthotopic growth and metastasis of bladder cancer in mice by alterations of cancer cell proliferation and apoptosis and tumor angiogenesis



Cancer Research 66(3): 1851-1858



A role of dietary bioactive components in bladder cancer prevention is biologically plausible because most substances or metabolites are excreted through the urinary tract and are consequently in direct contact with the mucosa of the bladder. We first determined antigrowth activity of genistein against poorly differentiated 253J B-V human bladder cancer cells in vitro.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 004474716

Download citation: RISBibTeXText

PMID: 16452247

DOI: 10.1158/0008-5472.can-05-1332


Related references

Relativity of tumor angiogenesis, cell proliferation, and apoptosis in bladder cancer of mice. Journal of China Medical University 34(1): 36-37, 2005

Effect of inhibiting tumor angiogenesis on cell proliferation and apoptosis in mice with bladder cancer. Journal of China Medical University 32(2): 148-150, 2003

Relationship between tumor angiogenesis and tumor cell apoptosis and proliferation in bladder cancer. Journal of China Medical University 33(5): 438-439, 2004

Expression of miRNAs involved in angiogenesis, tumor cell proliferation, tumor suppressor inhibition, epithelial-mesenchymal transition and activation of metastasis in bladder cancer. Journal of Urology 188(2): 615-623, 2013

Kaempferol suppresses bladder cancer tumor growth by inhibiting cell proliferation and inducing apoptosis. Molecular Carcinogenesis 54(9): 831-840, 2015

A patient-derived orthotopic xenograft model enabling human high-grade urothelial cell carcinoma of the bladder tumor implantation, growth, angiogenesis, and metastasis. Oncotarget 9(66): 32718-32729, 2018

Connective tissue growth factor-specific antibody attenuates tumor growth, metastasis, and angiogenesis in an orthotopic mouse model of pancreatic cancer. Molecular Cancer Therapeutics 5(5): 1108-1116, 2006

Spica prunellae promotes cancer cell apoptosis, inhibits cell proliferation and tumor angiogenesis in a mouse model of colorectal cancer via suppression of stat3 pathway. Bmc Complementary and Alternative Medicine 13: 144, 2014

Four resections for hepatic metastasis from gastric cancer: Histochemical analysis of cell proliferation, apoptosis, and angiogenesis. Journal of Gastroenterology 35(2): 150-154, 2000

Combretastatin A-4 inhibits cell growth and metastasis in bladder cancer cells and retards tumour growth in a murine orthotopic bladder tumour model. British Journal of Pharmacology 160(8): 2008-2027, 2010

Angiogenesis Inhibitor O-(Chloroacetyl-carbamoyl) fumagillol (TNP-470) Inhibits Tumor Angiogenesis, Growth and Spontaneous Metastasis of MKL-4 Human Breast Cancer Cells in Female Athymic Nude Mice. Breast Cancer 1(2): 109-115, 1994

Vascular endothelial growth factor expression in progression of cervical cancer: correlation with thymidine phosphorylase expression, angiogenesis, tumor cell proliferation, and apoptosis. Anticancer Research 20(2b): 1317-1322, 2000

Combined MEK and VEGFR inhibition in orthotopic human lung cancer models results in enhanced inhibition of tumor angiogenesis, growth, and metastasis. Clinical Cancer Research 18(6): 1641-1654, 2012

Angiogenesis and tumor proliferation/metastasis of human colorectal cancer cell line SW620 transfected with endocrine glands-derived-vascular endothelial growth factor, as a new angiogenic factor. Cancer Research 64(6): 1906-1910, 2004

Inhibition of tumor growth and metastasis of colon cancer in nude mice by angiogenesis inhibitor. Proceedings of the American Association for Cancer Research Annual Meeting 37(0): 61, 1996