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Neuroprotective effects of N-acetylcysteine on experimental closed head trauma in rats



Neuroprotective effects of N-acetylcysteine on experimental closed head trauma in rats



Neurochemical Research 31(4): 473-481



N-acetylcysteine (NAC) is a precursor of glutathione, a potent antioxidant, and a free radical scavenger. The beneficial effect of NAC on nervous system ischemia and ischemia/reperfusion models has been well documented. However, the effect of NAC on nervous system trauma remains less understood. Therefore, we aimed to investigate the therapeutic efficacy of NAC with an experimental closed head trauma model in rats.

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Accession: 004521020

Download citation: RISBibTeXText

PMID: 16758355

DOI: 10.1007/s11064-006-9040-z


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