Section 5
Chapter 4,566

A comparison of the susceptibility to praziquantel of schistosoma haematobium schistosoma japonicum schistosoma mansoni schistosoma intercalatum and schistosoma mattheei in hamsters

Webbe, G.; James, C.

Zeitschrift fuer Parasitenkunde 52(2): 169-178


Accession: 004565099

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Groups of 6-8 wk old hamsters each experimentally infected with Sudanese and South African strains of S. haematobium, Puerto Rican and Liberian strains of S. mansoni, S. japonicum from mainland China, a Congo strain of S. intercalatum and a Nelspruit South African strain of S. mattheei were treated with different dosage regimens of a new schistosomicide, praziquantel. This new compound exhibits a high degree of activity against the 3 major schistosome species, S. haematobium, S. japonicum and S. mansoni, against S. intercalatum and against the cattle schistosome S. mattheei in the hamster, with no apparent significant differences in efficacy against the different geographical strains of the parasites used in the trials.