+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

A correlative study of cytology and carcino embryonic antigen determination in cerebro spinal fluid in the diagnosis of breast cancer cerebro meningeal metastases



A correlative study of cytology and carcino embryonic antigen determination in cerebro spinal fluid in the diagnosis of breast cancer cerebro meningeal metastases



Archives d'Anatomie et de Cytologie Pathologiques 29(5): 287-290



The detection of carcinoembryonic antigen(CEA)-like substances in cerebrospinal fluid (CSF) of adult patients with cerebromeningeal tumors or involvement was evaluated in conjunction with cytodiagnosis in the detection of cerebrospinal metastases of breast cancer. Fifty-three breast cancer patients under evaluation for brain metastasis or in the follow-up of known lesions were investigated. Patients (21) had neither malignant cells nor CEA in their CSF. Women (32) had proven cerebromeningeal malignancy. Of these 32 metastatic cases, cytodiagnostic and/or CEA determination were positive in 21 cases at the 1st CSF examination. An interesting finding was the detection in 4 patients of an abnormal CEA level before the diagnosis of metastasis (1-4 mo.). CEA research in CSF may be a useful adjunct of cytological methods in the detection of cerebromeningeal metastases in breast cancer patients.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 004568413

Download citation: RISBibTeXText

PMID: 7305463


Related references

Cerebro spinal fluid carcino embryonic antigen in meningeal carcinomatosis from breast cancer. Journal of the American Medical Association 244(14): 1601-1603, 1980

Carcino embryonic antigen in plasma cerebro spinal fluid and cystic fluid of patients with intra cranial tumors. Neurologia Medico-Chirurgica 19(11): 1095-1106, 1979

Diagnostic significance of nerve cells in human cerebro spinal fluid with particular reference to cerebro spinal fluid cytology in the brain death syndrome. Journal of Neurology 225(2): 109-118, 1981

The concentration of CYFRA 21-1, NSE and CEA in cerebro-spinal fluid can be useful indicators for diagnosis of meningeal carcinomatosis of lung cancer. Cancer Biomarkers 13(2): 123-130, 2014

Myeloma cells in cerebro spinal fluid cytology immuno cytology and electron microscopy in an unusual cerebro spinal immuno globulin a plasma cytoma. Zeitschrift fuer Neurologie 202(3): 229-240, 1972

Cerebro spinal fluid cytology in cerebro vascular disease. International Congress Series : 255, 1969

Quantitative imaging of cerebro spinal fluid dynamics in patients with meningeal metastases. Journal of Nuclear Medicine 22(6): P89, 1981

Significance of quantitative determination of immuno globulin and albumin in cerebro spinal fluid and serum for evaluation to positive syphilis tests in cerebro spinal fluid. Zentralblatt fuer Bakteriologie Parasitenkunde Infektionskrankheiten und Hygiene Erste Abteilung Originale Reihe A Medizinische Mikrobiologie und Parasitologie 243(4): 439-440, 1979

Meningeal gliomatosis with negative cerebro spinal fluid cytology the value of glial fibrillary acid protein staining. Neurology 34(3 SUPPL 1): 277, 1984

Computed tomography and cerebro spinal fluid cytology in gross meningeal spreading of a recently operated medullo blastoma. Aktuelle Neurologie 8(2): 82-84, 1981

Cryptococcal meningitis with false positive cytology in the cerebro spinal fluid use of thymus derived cell rosetting to exclude meningeal lymphoma. Journal of the American Medical Association 239(22): 2369-2370, 1978

Tumor diagnosis by cytology of cerebro spinal fluid. Penzholz, H Et Al (Ed ) Advances in Neurosurgery, Vol 3 Brain Hypoxia, Pain 26th Annual Meeting Of The Deutsche Gesellschaft Fuer Neurochirurgie (German Society Of Neurosurgery) Heidelberg, West Germany, May 1-3, Xvii+460p Illus Springer-Verlag: Berlin, West Germany; New York, N Y , Usa ISBN 3-540-07466-X; ISBN 0-387-07466-X: 420-424, 1975

Meningeal carcinomatosis 21 years following bronchiolo alveolar carcinoma diagnosis by cisternal cerebro spinal fluid examination. Cancer 49(1): 1730S-176, 1982

The agar chamber a new method for cytology and protein determination in cerebro spinal fluid. Nervenarzt 43(11): 590-592, 1972

Usefulness of the determination of phospho hexose isomerase and carcino embryonic antigen in the early detection of metastases of breast cancer. Peeters, H (Ed ) Protides Of The Biological Fluids Colloquium, Vol 31 An International Review Series Devoted to Proteins And Related Studies; Proceedings, L983 Xxxi+1112p Pergamon Press: Oxford, England; New York, N Y , Usa Illus P571-574, 1984